Patients who suffer from mastocytosis disease can be diagnosed in different ways. Each diagnosis varies on the characteristics of the ailment as portrayed by the symptoms the patient experienced. Subsequently introduced are the typical medical tests performed for disease identification and confirmation.

1. CBC Count
CBC count is a diagnosis that is specifically intended for conditions associated with systemic mastocytosis. Such test will help disclose certain conditions like leukocytosis, anemia, eosinophilia and thrombocytopenia.

2. Total Tryptase Level Test
Tryptase serves as an indicator of the mast cell defragmentation that is separately generated with histamine. The total tryptase levels in plasma are linked with the solidity of mass cells of those systemic mastocytosis-suffering patients, bearing the symptoms of urticaria pigmentosa lesions. These are usually occurring in adult beings.

3. Laboratory Test
This is a commonly utilized study in mastocytosis patients suffering from urticaria pigmentosa disorder. Patients are to be diagnosed basing on their medical history, likewise on the physical examination results that manifest the correlation between the appearing lesions and the Darier syndrome. To confirm such condition, biopsies are typically required.

4. Urinary Histamine Level and Plasma Test
Such is a diagnosis for patients experiencing widespread lesions of cutaneous classification. Patients may undergo a urine histamine secretion in 24 hours, at around twice or thrice the normal urine histamine level.

Other mastocytosis conditions may require imaging test, as such with radiologic survey and bone scan. These types of diagnoses are only performed to non-pediatric patients who endure symptoms associated with the skeletal system disorders, including osteoporosis, lytic bone lesions ad the like.