A mole that is suspected to be malignant is first and foremost examined by removing it under local anesthesia and analyzed by a pathologist. If malignancy is confirmed, treatment would vary based upon the depth of the cancer in the skin and based upon whether it has spread to other parts of the skin. If there is just one mole that seems to be a cancerous mole, and if, on removal, it has been proved to be in the early stages of cancer, there might not need to be any further treatment. However, in the case of the cancerous moles spreading, radiotherapy or chemotherapy are the common treatments that have proven effective. These treatments are usually used when the chances of recurrence are very high. In some patients with advanced cancerous moles, interleukins are used as part of treatment. These interleukins are growth factors for T-cells, which destroy cancerous cells and have been noted to have good results in most cases.  In other cases, anticancer drugs such as fotemustine, dacarbazine and temozolomide are used, and have been successful in treating cancerous moles. Treatment of cancerous moles is most effective when detection of malignancy is early and treatment commences in the early stages.